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KMID : 1001920120520030221
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Journal of Korean Neurosurgical Society
2012 Volume.52 No. 3 p.221 ~ p.227
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Surgical Outcome of Spinal Cord Hemangioblastomas
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Park Chang-Hyun
Lee Chang-Hyun
Hyun Seung-Jae
Jahng Tae-Ahn
Kim Hyun-Jib
Kim Ki-Jeong
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Abstract
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Objective: Spinal cord hemangioblastomas are rare tumors. Despite their benign, slow-growing nature, they can cause severe neurological consequences. The purpose of this study was to evaluate variable factors, including clinical features, tumor findings, the extent of resection, and its recurrence or progression, which determine postoperative functional outcomes.
Methods: This study included sixteen patients at our institute who underwent microsurgical resection for sporadic spinal intramedullary hemangioblastomas and spinal intramedullary hemangioblastomas associated with von Hippel-Lindau (VHL) disease, between June 2003 and March 2012.
Results: A total of 30 operations were performed. Total resection (TR) of the tumor was achieved in 10 patients, and subtotal resection (STR) was achieved in 6. Postoperatively, the initial presenting symptoms were improved in 18.7% of the patients and were unchanged in 56.3%, but 25% were worse. Stable postoperative neurological functions were found in 83% of patients with preoperative McCormick grade I, and TR was achieved in 75% of these patients. In the STR group, poorer neurological status was observed in one patient, despite multiple operations. There were no poorer outcomes in the four cases of VHL disease. Various factors were analyzed, but only a correlation between the pre- and postoperative neurological status was verified in the TR-group patients.
Conclusion: Preoperative focal neurological impairment and meticulous microsurgical manipulation may be predictors of favorable outcomes for solitary hemangioblastomas. In addition, the preservation of function is more important than the extent of resection in VHL disease.
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KEYWORD
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Hemangioblastoma, Spinal cord, Functional outcome, Von Hippel-Lindau disease
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